Dexamethasone Induces a Transient Relative Cardiomegaly in Neonatal Rats

Dexamethasone and hydrocortisone in neonatal rats

P175: Neonatal Homocysteine Administration Induces Cerebellar Toxicity Via Oxidative Stress in Rats

Several in vitro studies have showed the neurotoxic effect of homocysteine (Hcy) to various neuronal types, including cerebellar Purkinje neurons. In this study, we investigated whether the Hcy has neurotoxic effects on the rat pup’s cerebellum in the postnatal period that it continues to development. Pups rats divided into control and Hcy group. Hcy administration (0.3–0.6 mmol/g b...

Moderate hyperbilirubinemia induces a transient alteration of neonatal behavior.

OBJECTIVE To investigate the behavioral changes induced by moderate hyperbilirubinemia in the otherwise healthy, untreated newborn infant. METHODS Fifty term neonates (23 boys) with untreated moderate hyperbilirubinemia (median: 14.3 mg/dL; range: 13.2-20 mg/dL) and 50 matched control subjects with lower bilirubin concentrations (median: 9.1 mg/dL; range: 5.3-12 mg/dL) were administered the B...

Coxsackie group B fatal neonatal myocarditis associated with cardiomegaly.

Most fatal cases of Coxsackie group B neonatal myocarditis have been associated with nursery epidemics. Occasional sporadic cases have been reported, mainly from the U.S.A., and a further case with gross cardiomegaly is described.

Neonatal handling induces anovulatory estrous cycles in rats.

Since previous work has shown that stimulation early in life decreases sexual receptiveness as measured by the female lordosis quotient, we suggested that neonatal handling could affect the function of the hypothalamus-pituitary-gonadal axis. The effects of neonatal handling on the estrous cycle and ovulation were analyzed in adult rats. Two groups of animals were studied: intact (no manipulati...